ID   PER-490
AC   CVCL_W986
AS   CVCL_IY98
SY   PER-490A
DR   Wikidata; Q54947203
RX   PubMed=12883040;
RX   PubMed=17117183;
RX   PubMed=27443263;
RX   PubMed=33937032;
CC   Doubling time: 97 hours (PubMed=17117183); 72 hours (PubMed=27443263).
CC   Omics: Transcriptomics; Microarray.
CC   Omics: Transcriptomics; RNAseq.
CC   Miscellaneous: Sampling site from personal communication of Kotecha, Rishi S.
CC   Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
ST   Source(s): PubMed=17117183; PubMed=27443263; PubMed=33937032
ST   Amelogenin: X
ST   CSF1PO: 11
ST   D13S317: 11,12
ST   D16S539: 11,12
ST   D18S51: 12,17
ST   D19S433: 13,15
ST   D21S11: 31,33.2
ST   D2S1338: 23,26
ST   D3S1358: 15,17
ST   D5S818: 11,12
ST   D7S820: 10,11
ST   D8S1179: 12,14
ST   FGA: 22,24
ST   TH01: 6,9.3
ST   TPOX: 8
ST   vWA: 15,17
DI   NCIt; C122617; Infant acute lymphoblastic leukemia with MLL rearrangement
DI   ORDO; Orphanet_513; Acute lymphoblastic leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   9D
CA   Cancer cell line
DT   Created: 17-07-14; Last updated: 10-04-25; Version: 12
//
RX   PubMed=27443263; DOI=10.1038/leu.2016.165; PMCID=PMC5220136;
RA   Cruickshank, Mark Nicholas
RA   Ford, Jette
RA   Cheung, Laurence C.
RA   Heng, Jasmin
RA   Singh, Sajla
RA   Wells, John
RA   Failes, Timothy W.
RA   Arndt, Greg M.
RA   Smithers, Nicholas
RA   Prinjha, Rabinder Kumar
RA   Anderson, Denise
RA   Carter, Kim Warwick
RA   Gout, Alexander M.
RA   Lassmann, Timo
RA   O'Reilly, John
RA   Cole, Catherine Helen
RA   Kotecha, Rishi S.
RA   Kees, Ursula R.
RT   "Systematic chemical and molecular profiling of MLL-rearranged infant
RT   acute lymphoblastic leukemia reveals efficacy of romidepsin.";
RL   Leukemia 31:40-50(2017).
//
RX   PubMed=33937032; DOI=10.3389/fonc.2021.631594; PMCID=PMC8082024;
RA   Cheung, Laurence C.
RA   de Kraa, Rebecca
RA   Oommen, Joyce
RA   Chua, Grace-Alyssa
RA   Singh, Sajla
RA   Hughes, Anastasia M.
RA   Ferrari, Emanuela
RA   Ford, Jette
RA   Chiu, Sung K.
RA   Stam, Ronald W.
RA   Kees, Ursula R.
RA   Malinge, Sebastien
RA   Kotecha, Rishi S.
RT   "Preclinical evaluation of carfilzomib for infant KMT2A-rearranged
RT   acute lymphoblastic leukemia.";
RL   Front. Oncol. 11:631594.1-631594.13(2021).
//
RX   PubMed=12883040;
RA   Kees, Ursula R.
RA   Ford, Jette
RA   Watson, Marcia
RA   Murch, Ashleigh R.
RA   Ringner, Markus
RA   Walker, Robert L.
RA   Meltzer, Paul S.
RT   "Gene expression profiles in a panel of childhood leukemia cell lines
RT   mirror critical features of the disease.";
RL   Mol. Cancer Ther. 2:671-677(2003).
//
RX   PubMed=17117183; DOI=10.1038/sj.bjc.6603447; PMCID=PMC2360743;
RA   Beesley, Alex H.
RA   Palmer, Misty-Lee
RA   Ford, Jette
RA   Weller, Richard E.
RA   Cummings, Aaron J.
RA   Freitas, Joseph R.
RA   Firth, Martin J.
RA   Perera, Kanchana U.
RA   de Klerk, Nick H.
RA   Kees, Ursula R.
RT   "Authenticity and drug resistance in a panel of acute lymphoblastic
RT   leukaemia cell lines.";
RL   Br. J. Cancer 95:1537-1544(2006).
//