ID   IMSUTi002-A-2
AC   CVCL_C9HE
SY   7F3955-KMT2A-AFF1; CRIEPIi003-A-2
DR   hPSCreg; IMSUTi002-A-2
DR   Wikidata; Q123032699
RX   PubMed=37639801;
CC   From: Sustainable System Research Laboratory, Central Research Institute of Electric Power Industry (CRIEPI); Chiba; Japan.
CC   Population: Japanese.
CC   Characteristics: Transfected with a Tet-on system so as to induce the expression of EGFP and the KMT2A-AFF1 fusion protein with the addition of doxycycline to the culture medium (PubMed=37639801).
CC   Genetic integration: Method=Transfection; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
CC   Genetic integration: Method=Transfection; Gene=HGNC; HGNC:7135; AFF1 (Note=KMT2-AFF1/MLL-AF4 fusion).
CC   Genetic integration: Method=Transfection; Gene=HGNC; HGNC:7132; KMT2A (Note=KMT2-AFF1/MLL-AF4 fusion).
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P04483; Escherichia coli Tn10 tetR.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P06492; Human herpesvirus 1 (HHV-1) VP16 (UL28) (Note=With p.Met1_Arg360del).
CC   Derived from site: In situ; Skin, epidermis; UBERON=UBERON_0001003.
CC   Cell type: Keratinocyte; CL=CL_0000312.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_XI76 ! IMSUTi002-A
SX   Male
AG   Age unspecified
CA   Induced pluripotent stem cell
DT   Created: 05-10-23; Last updated: 14-08-25; Version: 6
//
RX   PubMed=37639801; DOI=10.1016/j.scr.2023.103185;
RA   Takahashi, Masayuki
RT   "Generation of a human induced pluripotent stem cell line harboring
RT   the infant leukemia-associated fusion gene, KMT2A-AFF1
RT   (IMSUTi002-A-2).";
RL   Stem Cell Res. 71:103185-103185(2023).
//